Drug General Information
Drug ID
D03XGO
Former ID
DIB016589
Drug Name
Nematode anticoagulant proteins
Synonyms
NAP-5; NAP-6; NAPs, Corvas; Nematode anticoagulant proteins, Corvas; RNAP-5; NAP-A, Corvas; NAP-B, Corvas
Indication Angina pectoris [ICD9: 413; ICD10:I20] Terminated [546177]
Company
Dendreon San Diego LLC
Target and Pathway
Target(s) Coagulation factor Xa Target Info Modulator
KEGG Pathway Complement and coagulation cascades
PANTHER Pathway Blood coagulation
Pathway Interaction Database Beta2 integrin cell surface interactions
PathWhiz Pathway Coagulation
Reactome Extrinsic Pathway of Fibrin Clot Formation
Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
Gamma-carboxylation of protein precursors
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Removal of aminoterminal propeptides from gamma-carboxylated proteins
WikiPathways Complement and Coagulation Cascades
Human Complement System
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
Blood Clotting Cascade
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 546177Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006763)

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.