Drug Information

Drug General Information
Drug ID
D03YRN
Former ID
DIB020433
Drug Name
MRS2578
Synonyms
MRS-2578; MRS 2578
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539105]
Structure
Download
2D MOL
Formula
C20H20N6S4
InChI
InChI=1S/C20H20N6S4/c27-13-23-15-5-3-7-17(11-15)25-19(29)21-9-1-2-10-22-20(30)26-18-8-4-6-16(12-18)24-14-28/h3-8,11-12H,1-2,9-10H2,(H2,21,25,29)(H2,22,26,30)
InChIKey
QOHNRGHTJPFMSL-UHFFFAOYSA-N
PubChem Compound ID
16078986
PubChem Substance ID
24724530, 26753205, 28689788, 29215128, 29962708, 57379813, 85229961, 91721398, 124971573, 135650661, 135698631, 136367869, 144116254, 144221024, 152344182, 162009798, 162205083, 162248581, 163126274, 172914190, 184604079, 186022465, 204366632, 208265202, 223400740, 241375788, 242059859, 243428916, 252156312, 252160518, 252215850
Target and Pathway
Target(s) P2Y purinoceptor 6 Target Info Antagonist [527038]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome G alpha (q) signalling events
P2Y receptors
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 539105(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1753).
Ref 527038Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors. Biochem Pharmacol. 2004 May 1;67(9):1763-70.

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