Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03YVQ
|
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| Former ID |
DIB021077
|
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| Drug Name |
TRAM-34
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C22H17ClN2
|
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| InChI |
InChI=1S/C22H17ClN2/c23-21-15-8-7-14-20(21)22(25-17-9-16-24-25,18-10-3-1-4-11-18)19-12-5-2-6-13-19/h1-17H
|
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| InChIKey |
KBFUQFVFYYBHBT-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
854029, 9268120, 14925089, 29217667, 50111720, 57408414, 71825456, 75409114, 91616312, 103654538, 104121165, 109693504, 113528168, 117682952, 118049510, 134346051, 135651273, 135698750, 137018275, 139724138, 143295681, 152159547, 160839807, 162117177, 162249125, 162486666, 163402143, 164825256, 170558942, 174006257, 175424207, 185988345, 204428698, 210274869, 210280503, 223376400, 223442254, 223496591, 223556723, 226426227, 242068329, 243645457, 249741150, 249846675, 250177573, 250195072, 251899788, 252040542, 252156894, 252313183
|
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| Target and Pathway | |||||
| Target(s) | KCa3.1 | Target Info | Blocker (channel blocker) | [2] | |
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2336). | ||||
| REF 2 | Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis. Circulation. 2003 Sep 2;108(9):1119-25. Epub 2003 Aug 25. | ||||
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