TTD | Drug: D04DBR

Drug General Information
Drug ID	D04DBR
Former ID	DIB018524
Drug Name	2,2'-pyridylisatogen tosylate
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539080]
Structure		Download 2D MOL
Formula	C20H16N2O5S
InChI	InChI=1S/C13H8N2O2.C7H8O3S/c16-13-9-5-1-2-7-11(9)15(17)12(13)10-6-3-4-8-14-10;1-6-2-4-7(5-3-6)11(8,9)10/h1-8H;2-5H,1H3,(H,8,9,10)
InChIKey	MMPTYEXNPWSTOR-UHFFFAOYSA-N
PubChem Compound ID	124333
PubChem Substance ID	10241048, 11114297, 29304398, 57340859, 77155017, 103106691, 104420586, 117632990, 126435434, 135649681, 135698560, 162023353, 162548177, 172870672, 241098747, 241182623, 241375578, 242175681, 249617372
Target and Pathway
Target(s)	P2Y purinoceptor 1	Target Info	Modulator (allosteric modulator)	[527106]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	Platelet activation
Reactome	G alpha (q) signalling events
	P2Y receptors
	ADP signalling through P2Y purinoceptor 1
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539080	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1729).
Ref 527106	2,2'-Pyridylisatogen tosylate antagonizes P2Y1 receptor signaling without affecting nucleotide binding. Biochem Pharmacol. 2004 Jul 15;68(2):231-7.

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Drug Information