Drug General Information
Drug ID
D04PER
Former ID
DIB005187
Drug Name
XEN-402
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Phase 2 [523154]
Company
Xenon Pharmaceuticals Inc
Structure
Download
2D MOL

3D MOL

Target and Pathway
Target(s) Voltage-gated sodium channel subunit alpha Nav1.7 Target Info Inhibitor [531677]
Reactome Interaction between L1 and Ankyrins
References
Ref 523154ClinicalTrials.gov (NCT01195636) A Crossover Study to Evaluate the Safety, Tolerability and Efficacy of XPF-002 in Subjects With Postherpetic Neuralgia (PHN). U.S. National Institutes of Health.
Ref 531677Treatment of Na(v)1.7-mediated pain in inherited erythromelalgia using a novel sodium channel blocker. Pain. 2012 Jan;153(1):80-5.

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