Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05DXT
|
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| Former ID |
DIB016833
|
||||
| Drug Name |
XEN-D0103
|
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| Synonyms |
KCNA voltage-gated potassium channel-5 inhibitor (atrial fibrillation), Xention
|
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| Indication | Atrial fibrillation [ICD9: 272, 427.31; ICD10:E78, I48] | Phase 1 | [1] | ||
| Company |
Xention Ltd
|
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| Target and Pathway | |||||
| Target(s) | Potassium voltage-gated channel subfamily A member 5 | Target Info | Inhibitor | [2] | |
| PathWhiz Pathway | Muscle/Heart Contraction | ||||
| Reactome | Voltage gated Potassium channels | ||||
| WikiPathways | Potassium Channels | ||||
| References | |||||
| REF 1 | ClinicalTrials.gov (NCT02390258) Fed-Fasted, Single and Multiple Ascending Dose Trial of XEN-D0103. U.S. National Institutes of Health. | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 542). | ||||
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