Drug General Information
Drug ID	D05EOW
Former ID	DIB019732
Drug Name	diarylpropionitril
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539867]
Structure		Download 2D MOL
Formula	C15H13NO2
InChI	InChI=1S/C15H13NO2/c16-10-13(12-3-7-15(18)8-4-12)9-11-1-5-14(17)6-2-11/h1-8,13,17-18H,9H2
InChIKey	GHZHWDWADLAOIQ-UHFFFAOYSA-N
PubChem Compound ID	102614
PubChem Substance ID	4787349, 10232684, 15366572, 44432490, 50025873, 53790406, 53790908, 53801030, 75849427, 85787611, 91746498, 103371140, 104002116, 104367338, 125335435, 135059361, 135330769, 135610547, 162023054, 163134280, 206252313, 216088074, 228103496, 241182477, 242797341, 252159976, 252457911, 252467477
Target and Pathway
Target(s)	Estrogen receptor beta	Target Info	Agonist	[526191]
KEGG Pathway	Estrogen signaling pathway
	Prolactin signaling pathway
Pathway Interaction Database	Plasma membrane estrogen receptor signaling
	Validated nuclear estrogen receptor beta network
	Validated nuclear estrogen receptor alpha network
Reactome	Nuclear Receptor transcription pathway
WikiPathways	SIDS Susceptibility Pathways
	Ovarian Infertility Genes
	Integrated Pancreatic Cancer Pathway
	Nuclear Receptors
References
Ref 539867	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2825).
Ref 526191	Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. J Med Chem. 2001 Nov 22;44(24):4230-51.

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