Drug Information
Drug General Information | |||||
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Drug ID |
D05FFY
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Former ID |
DNC004483
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Drug Name |
1-(4-Cyanobenzyl)-5-methyl-1H-imidazole
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Synonyms |
4-(5-Methyl-imidazol-1-ylmethyl)-benzonitrile
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Indication | Discovery agent | Investigative | [530679] | ||
Structure |
Download2D MOL |
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Canonical SMILES |
CC1=CN=CN1CC2=CC=C(C=C2)C#N
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InChI |
1S/C12H11N3/c1-10-7-14-9-15(10)8-12-4-2-11(6-13)3-5-12/h2-5,7,9H,8H2,1H3
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InChIKey |
JYTDMONWVZXEMX-UHFFFAOYSA-N
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Target and Pathway | |||||
Target(s) | Cytochrome P450 11B1, mitochondrial | Target Info | Inhibitor | [530679] | |
Cytochrome P450 19 | Target Info | Inhibitor | [529291] | ||
NetPath Pathway | FSH Signaling Pathway | ||||
PANTHER Pathway | Androgen/estrogene/progesterone biosynthesis | ||||
PathWhiz Pathway | SteroidogenesisPW000045:Androgen and Estrogen Metabolism | ||||
WikiPathways | Metapathway biotransformation | ||||
Oxidation by Cytochrome P450 | |||||
Metabolism of steroid hormones and vitamin D | |||||
Corticotropin-releasing hormoneWP702:Metapathway biotransformation | |||||
Tryptophan metabolism | |||||
Ovarian Infertility Genes | |||||
FSH signaling pathway | |||||
Integrated Breast Cancer Pathway | |||||
Phase 1 - Functionalization of compounds | |||||
References | |||||
Ref 529291 | J Med Chem. 1991 Feb;34(2):725-36.Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease. | ||||
Ref 530679 | J Med Chem. 2010 Feb 25;53(4):1712-25.Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). |
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