Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05GQK
|
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| Former ID |
DIB020812
|
||||
| Drug Name |
R-L3
|
||||
| Synonyms |
R-L364,373
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C25H20FN3O
|
||||
| InChI |
InChI=1S/C25H20FN3O/c1-29-23-13-7-4-10-19(23)24(18-9-2-5-11-20(18)26)28-22(25(29)30)14-16-15-27-21-12-6-3-8-17(16)21/h2-13,15,22,27H,14H2,1H3/t22-/m1/s1
|
||||
| InChIKey |
CGBANSGENFERAT-JOCHJYFZSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Potassium voltage-gated channel subfamily KQT member 1 | Target Info | Activator | [2] | |
| KEGG Pathway | Adrenergic signaling in cardiomyocytes | ||||
| Cholinergic synapse | |||||
| Gastric acid secretion | |||||
| Pancreatic secretion | |||||
| Protein digestion and absorption | |||||
| Vibrio cholerae infection | |||||
| PathWhiz Pathway | Muscle/Heart Contraction | ||||
| Reactome | Voltage gated Potassium channels | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Potassium Channels | |||||
| miR-targeted genes in muscle cell - TarBase | |||||
| miR-targeted genes in lymphocytes - TarBase | |||||
| TarBasePathway | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2595). | ||||
| REF 2 | A novel benzodiazepine that activates cardiac slow delayed rectifier K+ currents. Mol Pharmacol. 1998 Jul;54(1):220-30. | ||||
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