Drug General Information
Drug ID	D05HJP
Former ID	DNC005664
Drug Name	4-Inden-(1E)-ylidenemethyl-phenylamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527501]
Structure		Download 2D MOL 3D MOL
Formula	C16H13N
Canonical SMILES	C1=CC=C2C(=C1)C=CC2=CC3=CC=C(C=C3)N
InChI	1S/C16H13N/c17-15-9-5-12(6-10-15)11-14-8-7-13-3-1-2-4-16(13)14/h1-11H,17H2/b14-11+
InChIKey	GISMNWZLKDONAA-SDNWHVSQSA-N
PubChem Compound ID	6476992
Target and Pathway
Target(s)	5-hydroxytryptamine 6 receptor	Target Info	Inhibitor	[527501]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 527501	Bioorg Med Chem Lett. 2005 Apr 15;15(8):1987-91.Binding of isotryptamines and indenes at h5-HT6 serotonin receptors.
Ref 527501	Bioorg Med Chem Lett. 2005 Apr 15;15(8):1987-91.Binding of isotryptamines and indenes at h5-HT6 serotonin receptors.

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