Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05HNB
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| Former ID |
DNC003689
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| Drug Name |
LY-282210
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C30H28O10
|
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| Canonical SMILES |
CCC1=C(C=C(C(=C1)C(=O)C)O)OCCCOC2=C(C3=C(C=C2)C(=O)C4=C<br />(O3)C=CC(=C4)C(=O)O)CCC(=O)O
|
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| InChI |
1S/C30H28O10/c1-3-17-13-21(16(2)31)23(32)15-26(17)39-12-4-11-38-24-9-6-20-28(35)22-14-18(30(36)37)5-8-25(22)40-29(20)19(24)7-10-27(33)34/h5-6,8-9,13-15,32H,3-4,7,10-12H2,1-2H3,(H,33,34)(H,36,37)
|
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| InChIKey |
HGMXXGVRUCAMMK-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Leukotriene B4 receptor 2 | Target Info | Inhibitor | [1] | |
| Leukotriene B4 receptor 1 | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interaction | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PANTHER Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | ||||
| Reactome | Leukotriene receptors | ||||
| G alpha (q) signalling eventsR-HSA-391906:Leukotriene receptors | |||||
| G alpha (q) signalling events | |||||
| WikiPathways | Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, OtherWP80:Nucleotide GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Spinal Cord Injury | |||||
| References | |||||
| REF 1 | J Med Chem. 1993 Nov 26;36(24):3982-4.Biphenylyl-substituted xanthones: highly potent leukotriene B4 receptor antagonists. | ||||
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