Drug Information
Drug General Information | |||||
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Drug ID |
D05HZI
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Former ID |
DNC000918
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Drug Name |
MDL 101,731
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Drug Type |
Small molecular drug
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Indication | Gastric cancer [ICD9: 151; ICD10:C16] | Discontinued in Phase 2 | [545234] | ||
Structure |
Download2D MOL |
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Formula |
C10H12FN3O4
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Canonical SMILES |
C1=CN(C(=O)N=C1N)C2C(=CF)C(C(O2)CO)O
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InChI |
1S/C10H12FN3O4/c11-3-5-8(16)6(4-15)18-9(5)14-2-1-7(12)13-10(14)17/h1-3,6,8-9,15-16H,4H2,(H2,12,13,17)/b5-3+/t6-,8+,9-/m1/s1
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InChIKey |
GFFXZLZWLOBBLO-ASKVSEFXSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Ribonucleoside-diphosphatereductase subunit M2 | Target Info | Modulator | ||
BioCyc Pathway | Pyrimidine deoxyribonucleotides biosynthesis from CTP | ||||
Pyrimidine deoxyribonucleotides de novo biosynthesis | |||||
Guanosine nucleotides de novo biosynthesis | |||||
Superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis | |||||
Superpathway of purine nucleotide salvage | |||||
Purine nucleotides de novo biosynthesis | |||||
Adenosine deoxyribonucleotides de novo biosynthesis | |||||
Guanosine deoxyribonucleotides de novo biosynthesis | |||||
NetPath Pathway | EGFR1 Signaling Pathway | ||||
Pathway Interaction Database | E2F transcription factor network | ||||
PathWhiz Pathway | Purine Metabolism | ||||
Pyrimidine Metabolism | |||||
References |
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