Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05ITB
|
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| Former ID |
DIB018568
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| Drug Name |
2-MPP
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C11H16N2O
|
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| InChI |
InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
|
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| InChIKey |
VNZLQLYBRIOLFZ-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
3133812, 4770344, 8151101, 11111755, 11342060, 11362243, 11363327, 11365889, 11368451, 11372162, 11374909, 11376613, 11485571, 11487645, 11489634, 11490847, 11492980, 11494247, 15195365, 24439688, 24883872, 24896714, 29200502, 33387276, 47440456, 47515509, 47589169, 47662493, 47810951, 48185167, 48334693, 48435393, 49832573, 50111250, 56369526, 57320877, 57566672, 58034553, 78526294, 85087612, 85209872, 85789274, 87572872, 87617886, 90341119, 92709722, 99216017, 103087881, 103154249, 103169108
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| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 7 receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | Ras signaling pathway | ||||
| Calcium signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| Serotonergic synapse | |||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| PathWhiz Pathway | Excitatory Neural Signalling Through 5-HTR 7 and Serotonin | ||||
| Reactome | Serotonin receptors | ||||
| G alpha (s) signalling events | |||||
| WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | ||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 280). | ||||
| REF 2 | Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. J Biol Chem. 1993 Aug 25;268(24):18200-4. | ||||
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