Drug Information

Drug General Information
Drug ID
D05ITB
Former ID
DIB018568
Drug Name
2-MPP
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539841]
Structure
Download
2D MOL
Formula
C11H16N2O
InChI
InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
InChIKey
VNZLQLYBRIOLFZ-UHFFFAOYSA-N
PubChem Compound ID
1346
PubChem Substance ID
3133812, 4770344, 8151101, 11111755, 11342060, 11362243, 11363327, 11365889, 11368451, 11372162, 11374909, 11376613, 11485571, 11487645, 11489634, 11490847, 11492980, 11494247, 15195365, 24439688, 24883872, 24896714, 29200502, 33387276, 47440456, 47515509, 47589169, 47662493, 47810951, 48185167, 48334693, 48435393, 49832573, 50111250, 56369526, 57320877, 57566672, 58034553, 78526294, 85087612, 85209872, 85789274, 87572872, 87617886, 90341119, 92709722, 99216017, 103087881, 103154249, 103169108
Target and Pathway
Target(s) 5-hydroxytryptamine 7 receptor Target Info Agonist [534019]
KEGG Pathway Ras signaling pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 539841(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 280).
Ref 534019Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. J Biol Chem. 1993 Aug 25;268(24):18200-4.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.