Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05IWY
|
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| Former ID |
DNC009266
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| Drug Name |
Gamma-mangostin
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [531095] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C23H24O6
|
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| Canonical SMILES |
CC(=CCC1=C(C2=C(C=C1CO)OC3=CC(=C(C(=C3C2=O)CC=C(C)C)O)O<br />)O)C
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| InChI |
1S/C24H26O6/c1-12(2)5-7-15-14(11-25)9-18-21(23(15)28)24(29)20-16(8-6-13(3)4)22(27)17(26)10-19(20)30-18/h5-6,9-10,25-28H,7-8,11H2,1-4H3
|
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| InChIKey |
HODIDERFBMZRHC-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cytochrome P450 19 | Target Info | Inhibitor | [529538] | |
| Neuraminidase | Target Info | Inhibitor | [531095] | ||
| NetPath Pathway | FSH Signaling Pathway | ||||
| PANTHER Pathway | Androgen/estrogene/progesterone biosynthesis | ||||
| PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
| Reactome | Endogenous sterols | ||||
| References | |||||
| Ref 529538 | J Nat Prod. 2008 Jul;71(7):1161-6. Epub 2008 Jun 18.Xanthones from the botanical dietary supplement mangosteen (Garcinia mangostana) with aromatase inhibitory activity. | ||||
| Ref 531095 | Bioorg Med Chem. 2010 Sep 1;18(17):6258-64. Epub 2010 Jul 19.Xanthones with neuraminidase inhibitory activity from the seedcases of Garcinia mangostana. | ||||
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