Drug Information

Drug General Information
Drug ID
D05JPG
Former ID
DNC005665
Drug Name
[2-(3-Benzyl-3H-inden-1-yl)-ethyl]-methyl-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527501]
Structure
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2D MOL

3D MOL
Formula
C19H21N
Canonical SMILES
CNCCC1=CC(C2=CC=CC=C21)CC3=CC=CC=C3
InChI
1S/C19H21N/c1-20-12-11-16-14-17(13-15-7-3-2-4-8-15)19-10-6-5-9-18(16)19/h2-10,14,17,20H,11-13H2,1H3
InChIKey
UHYPQIJLHJTNMK-UHFFFAOYSA-N
PubChem Compound ID
44401277
Target and Pathway
Target(s) 5-hydroxytryptamine 6 receptor Target Info Inhibitor [527501]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 527501Bioorg Med Chem Lett. 2005 Apr 15;15(8):1987-91.Binding of isotryptamines and indenes at h5-HT6 serotonin receptors.
Ref 527501Bioorg Med Chem Lett. 2005 Apr 15;15(8):1987-91.Binding of isotryptamines and indenes at h5-HT6 serotonin receptors.

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