Drug Information
Drug General Information | |||||
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Drug ID |
D05KEE
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Former ID |
DIB018763
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Drug Name |
AFD(R)
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539954] | ||
Structure |
Download2D MOL |
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Formula |
C18H32NO5P
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InChI |
InChI=1S/C18H32NO5P/c1-3-4-5-6-7-14-23-17-10-8-16(9-11-17)12-13-18(2,19)15-24-25(20,21)22/h8-11H,3-7,12-15,19H2,1-2H3,(H2,20,21,22)/t18-/m1/s1
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InChIKey |
NMRLBSIYIBOLLJ-GOSISDBHSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Sphingosine 1-phosphate receptor 5 | Target Info | Agonist | [526934] | |
Sphingosine-1-phosphate receptor-3 | Target Info | Agonist | [526319] | ||
S1P4 receptor | Target Info | Agonist | [526934] | ||
Sphingosine 1-phosphate receptor 1 | Target Info | Agonist | [526319] | ||
Pathway Interaction Database | S1P4 pathway | ||||
S1P5 pathway | |||||
Sphingosine 1-phosphate (S1P) pathways1p_s1p3_pathway:S1P3 pathway | |||||
Sphingosine 1-phosphate (S1P) pathwayfcer1pathway:Fc-epsilon receptor I signaling in mast cells | |||||
S1P3 pathway | |||||
S1P1 pathway | |||||
Sphingosine 1-phosphate (S1P) pathway | |||||
PDGFR-beta signaling pathway | |||||
References | |||||
Ref 526319 | The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J Biol Chem. 2002 Jun 14;277(24):21453-7. Epub 2002 Apr 19. | ||||
Ref 526934 | Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate. J Biol Chem. 2004 Apr 2;279(14):13839-48. Epub 2004 Jan 19. |
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