Drug General Information
Drug ID
D05KRC
Former ID
DIB009815
Drug Name
Emopamil
Synonyms
Levemopamil
Drug Type
Small molecular drug
Indication Cerebrovascular ischaemia [ICD9: 434.91; ICD10:I61-I63] Terminated [534257]
Company
Knoll GmbH
Structure
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2D MOL

3D MOL

Formula
C23H30N2
Canonical SMILES
C(C#N)(c1ccccc1)(C(C)C)CCCN(CCc1ccccc1)C
CAS Number
CAS 78370-13-5
PubChem Compound ID
Target and Pathway
Target(s) Calcium channel Target Info Modulator [534257]
5-HT 2 receptor Target Info Modulator [534257]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
References
Ref 534257Calcium entry and 5-HT2 receptor blockade in oliguric ischaemic acute renal failure: effects of levemopamil in conscious rats. Br J Pharmacol. 1996 Mar;117(6):1348-54.
Ref 534257Calcium entry and 5-HT2 receptor blockade in oliguric ischaemic acute renal failure: effects of levemopamil in conscious rats. Br J Pharmacol. 1996 Mar;117(6):1348-54.

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