Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05RWL
|
||||
| Former ID |
DIB013860
|
||||
| Drug Name |
NSD-788
|
||||
| Synonyms |
GABA-A receptor modulator (anxiety/depression), NeuroSearch
|
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| Indication | Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] | Phase 1 | [1] | ||
| Company |
NeuroSearch A/S
|
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| Target and Pathway | |||||
| Target(s) | GABA A receptor | Target Info | Modulator | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | |||||
| GABAergic synapse | |||||
| Morphine addiction | |||||
| Nicotine addiction | |||||
| Reactome | Ligand-gated ion channel transport | ||||
| GABA A receptor activation | |||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
| Iron uptake and transport | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028006) | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415). | ||||
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