Drug General Information
Drug ID	D05SAP
Former ID	DNC006791
Drug Name	N-(3-(aminomethyl)phenyl)benzenesulfonamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528373]
Structure		Download 2D MOL 3D MOL
Formula	C13H14N2O2S
Canonical SMILES	C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC(=C2)CN
InChI	1S/C13H14N2O2S/c14-10-11-5-4-6-12(9-11)15-18(16,17)13-7-2-1-3-8-13/h1-9,15H,10,14H2
InChIKey	RMWBQRLIFOIUFM-UHFFFAOYSA-N
PubChem Compound ID	11849791
Target and Pathway
Target(s)	5-hydroxytryptamine 6 receptor	Target Info	Inhibitor	[528373]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528373	J Med Chem. 2006 Aug 24;49(17):5217-25.Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors.
Ref 528373	J Med Chem. 2006 Aug 24;49(17):5217-25.Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors.

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