Drug Information
Drug General Information | |||||
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Drug ID |
D05ZWG
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Former ID |
DNC001320
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Drug Name |
Senktide
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C40H55N7O11S
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InChI |
InChI=1S/C40H55N7O11S/c1-24(2)19-28(37(55)45-27(36(41)54)17-18-59-4)44-33(49)23-42-39(57)31(21-26-13-9-6-10-14-26)47(3)40(58)30(20-25-11-7-5-8-12-25)46-38(56)29(22-35(52)53)43-32(48)15-16-34(50)51/h5-14,24,27-31H,15-23H2,1-4H3,(H2,41,54)(H,42,57)(H,43,48)(H,44,49)(H,45,55)(H,46,56)(H,50,51)(H,52,53)/t27-,28-,29-,30-,31-/m0/s1
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InChIKey |
HMHYXLVEFVGOPM-QKUYTOGTSA-N
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CAS Number |
CAS 189261-10-7
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Nigral tachykinin NK(3) receptor | Target Info | Agonist | [535700], [537952] | |
Reactome | G alpha (q) signalling events | ||||
References | |||||
Ref 533307 | Ovarian and hormonal responses to single or continuous peripheral administration of senktide, a neurokinin 3 receptor agonist, during the follicular phase in goats. Domest Anim Endocrinol. 2015 Oct;53:136-43. | ||||
Ref 539349 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2127). | ||||
Ref 535700 | Implication of nigral tachykinin NK3 receptors in the maintenance of hypertension in spontaneously hypertensive rats: a pharmacologic and autoradiographic study. Br J Pharmacol. 2003 Feb;138(4):554-63. | ||||
Ref 537952 | Neurokinin-3 receptors modulate dopamine cell function and alter the effects of 6-hydroxydopamine. Brain Res. 1995 Oct 9;695(1):19-24. |
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