Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06FWY
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| Former ID |
DNC006875
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| Drug Name |
KYS-05070
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C28H33N5O3S
|
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| Canonical SMILES |
CCN1C(C2=CC=CC=C2N=C1N(C)C)CC(=O)NCC3=CC=C(C=C3)NS(=O)(<br />=O)C4=CC=C(C=C4)C
|
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| InChI |
1S/C28H33N5O3S/c1-5-33-26(24-8-6-7-9-25(24)30-28(33)32(3)4)18-27(34)29-19-21-12-14-22(15-13-21)31-37(35,36)23-16-10-20(2)11-17-23/h6-17,26,31H,5,18-19H2,1-4H3,(H,29,34)
|
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| InChIKey |
UBFZYFFOQNFRPD-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Voltage-dependent T-type calcium channel alpha-1G subunit | Target Info | Inhibitor | [1] | |
| KEGG Pathway | MAPK signaling pathway | ||||
| Calcium signaling pathway | |||||
| Circadian entrainment | |||||
| Type II diabetes mellitus | |||||
| PANTHER Pathway | Endogenous cannabinoid signaling | ||||
| GABA-B receptor II signaling | |||||
| Nicotine pharmacodynamics pathway | |||||
| Pathway Interaction Database | Regulation of nuclear beta catenin signaling and target gene transcription | ||||
| PathWhiz Pathway | Muscle/Heart Contraction | ||||
| Reactome | NCAM1 interactions | ||||
| WikiPathways | NCAM signaling for neurite out-growth | ||||
| Nicotine Activity on Chromaffin Cells | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2006 Oct 1;16(19):5014-7. Epub 2006 Jul 28.Growth inhibition of human cancer cells in vitro by T-type calcium channel blockers. | ||||
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