Drug Information

Drug General Information
Drug ID
D06GJW
Former ID
DNC001033
Drug Name
Noradrenaline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [468073]
Structure
Download
2D MOL

3D MOL
Formula
C8H11NO3
InChI
InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2
InChIKey
SFLSHLFXELFNJZ-UHFFFAOYSA-N
CAS Number
CAS 51-41-2
PubChem Compound ID
951
PubChem Substance ID
146522, 219187, 3137157, 5633844, 8150886, 10318916, 10507475, 11534313, 15194998, 24439308, 47217070, 47365471, 49892615, 49892616, 51036043, 51075402, 57320616, 85209636, 85753313, 90341653, 103114946, 104296333, 104671918, 117616920, 118510068, 124749407, 125308191, 125351846, 125543283, 125617113, 126608921, 126632801, 126678538, 129228531, 134973927, 134975595, 135651526, 137001235, 140204844, 143512633, 162250799, 162871635, 164788400, 166426611, 176223939, 179116819, 198992584, 215780277, 223435936, 226395016
ChEBI ID
ChEBI:18357
SuperDrug ATC ID
C01CA03
SuperDrug CAS ID
cas=000051412
Target and Pathway
Target(s) Beta-1 adrenergic receptor Target Info Agonist [535812]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Gap junction
Salivary secretion
Dilated cardiomyopathy
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta1 adrenergic receptor signaling pathway
PathWhiz Pathway Muscle/Heart Contraction
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
Endothelin Pathways
GPCR ligand binding
GPCR downstream signaling
References
Ref 468073(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 484).
Ref 535812Classification of the beta-adrenoceptor subtype in the rat portal vein: effect of altered thyroid hormone levels. Eur J Pharmacol. 1992 Mar 3;212(2-3):201-7.

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