Drug Information

Drug General Information
Drug ID
D06HWI
Former ID
DNC007346
Drug Name
GNF-PF-1967
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528504]
Structure
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2D MOL

3D MOL
Formula
C30H34FN3O3
Canonical SMILES
CCN(CC)CCNC(=O)C1C(N(C(=O)C2=CC=CC=C12)CC3=CC=C(C=C3)F)<br />C4=CC=C(C=C4)OC
InChI
1S/C30H34FN3O3/c1-4-33(5-2)19-18-32-29(35)27-25-8-6-7-9-26(25)30(36)34(20-21-10-14-23(31)15-11-21)28(27)22-12-16-24(37-3)17-13-22/h6-17,27-28H,4-5,18-20H2,1-3H3,(H,32,35)
InChIKey
ACZABABCHZPYHY-UHFFFAOYSA-N
PubChem Compound ID
4617502
Target and Pathway
Target(s) Voltage-dependent T-type calcium channel subunit alpha-1H Target Info Inhibitor [528504]
KEGG Pathway MAPK signaling pathway
Calcium signaling pathway
Circadian entrainment
PathWhiz Pathway Muscle/Heart Contraction
Reactome NCAM1 interactions
WikiPathways Corticotropin-releasing hormone
NCAM signaling for neurite out-growth
References
Ref 528504Bioorg Med Chem. 2007 Jan 15;15(2):1091-105. Epub 2006 Oct 30.3D pharmacophore based virtual screening of T-type calcium channel blockers.
Ref 528504Bioorg Med Chem. 2007 Jan 15;15(2):1091-105. Epub 2006 Oct 30.3D pharmacophore based virtual screening of T-type calcium channel blockers.

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