Drug General Information
Drug ID
D06JGH
Former ID
DAP000804
Drug Name
Pyridoxal Phosphate
Synonyms
Biosechs; Codecarboxylase; Hairoxal; Hiadelon; Himitan; PLP; Phosphopyridoxal; Pidopidon; Piodel; Pydoxal; Pyrido; Pyromijin; Sechvitan; Vitazechs; Hexermin P; Phosphopyridoxal coenzyme; Phosphoridoxal coenzyme; Pyridoxal P; Pyridoxal monophosphate; Pyridoxal phosphate [JAN]; Pyridoxaldehyde phosphate; Pyridoxyl phosphate; Vitahexin P; Apolon B6; Coenzyme B6; SRI 2392; VITAMIN B6 COMPLEX; Vitamin B6 phosphate; Apolon B(sub 6); HI-Pyridoxin; Hexermin-P; Pal-P; Pyridoxal 5-monophosphoric acid ester; Pyridoxal 5-phosphate; Pyridoxal phosphate (6CI); Pyridoxal-5P; Pyridoxal-P; Sechvitan, Vitahexin P; Vitahexin-P; Vitamin B6 phosphate (ester); PYRIDOXAL-5-PHOSPHATE; Pyridoxal 5'-phosphate; Pyridoxal 5'-phosphate hydrate; Pyridoxal-5-Phosphate Hydrate; Pyridoxal-5-monophosphate; P-5'-P; Pyridoxal 5'-(dihydrogen phosphate); Pyridoxal 5'-phosphate monohydrate, vitamin B6; Pyridoxal 5'-phosphate monohydrate-Vitamin B6; Pyridoxal phosphate treated .beta.-lactoglobulin from bovine whey; Pyridoxal, 5-(dihydrogen phosphate); Pyridoxal, 5-(dihydrogenphosphate); Pyridoxal-5'-phosphate; Pyridoxal, 5-(dihydrogen phosphate) (8CI); Phosphoric acid mono-(4-formyl-5-hydroxy-6-methyl-pyridin-3-ylmethyl) ester; Isonicotinaldehyde, 3-hydroxy-5-(hydroxymethyl)-2-methyl-, 5-(dihydrogen phosphate); (4-Formyl-5-hydroxy-6-methyl(3-pyridyl))methyl dihydrogen phosphate; (4-formyl-5-hydroxy-6-methyl-3-pyridinyl)methyl dihydrogen phosphate; (4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate; 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine-5-calcium phosphate; 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine-5-calcium phosphate trihydrate; 2-Methyl-3-hydroxy-4-formyl-5-pyridylmethylphosphoric acid; 3-Hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde; 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate; 3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde; 4-Formyl-5-hydroxy-6-methyl-pyridin-3-yl)methoxyphosphonic acid; 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-(9CI)
Drug Type
Small molecular drug
Indication Dietary shortage [ICD9: 260-269; ICD10:E40-E46] Approved [540717], [550672]
Therapeutic Class
Dietary supplement
Structure
Download
2D MOL

3D MOL

Formula
C8H10NO6P
InChI
InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKey
NGVDGCNFYWLIFO-UHFFFAOYSA-N
CAS Number
CAS 54-47-7
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:18405
SuperDrug ATC ID
A11HA06
SuperDrug CAS ID
cas=000054477
Target and Pathway
Target(s) 4-aminobutyrate aminotransferase, mitochondrial Target Info Inhibitor [536555]
BioCyc Pathway GABA shunt
Valine degradation
Beta-alanine degradation
4-aminobutyrate degradation
KEGG Pathway Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine degradation
beta-Alanine metabolism
Propanoate metabolism
Butanoate metabolism
Metabolic pathways
GABAergic synapse
PANTHER Pathway Aminobutyrate degradation
Pyrimidine Metabolism
Gamma-aminobutyric acid synthesis
PathWhiz Pathway Aspartate Metabolism
Glutamate Metabolism
Beta-Alanine Metabolism
Valine, Leucine and Isoleucine Degradation
Propanoate Metabolism
WikiPathways GABA synthesis, release, reuptake and degradation
Alanine and aspartate metabolism
References
Ref 540717(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5249).
Ref 550672Drug information of Pyridoxal Phosphate, 2008. eduDrugs.
Ref 536555DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29.

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