| Drug General Information |
| Drug ID |
D06LED
|
| Former ID |
DNC003477
|
| Drug Name |
7,8-dihydroxy-4-phenyl-2H-chromen-2-one
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C15H10O4
|
| Canonical SMILES |
C1=CC=C(C=C1)C2=CC(=O)OC3=C2C=CC(=C3O)O
|
| InChI |
1S/C15H10O4/c16-12-7-6-10-11(9-4-2-1-3-5-9)8-13(17)19-15(10)14(12)18/h1-8,16,18H
|
| InChIKey |
JRVIIPJSVKTPBK-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
1096864, 3441879, 6898769, 11355229, 11673324, 24880861, 25622547, 39419758, 48111216, 56435695, 77801129, 84975604, 88500944, 92094532, 99293491, 99444520, 104250031, 113957547, 117614478, 124410039, 128318496, 135377049, 137495990, 160969104, 162920290, 163644386, 166235709, 170481947, 173895510, 176250875, 184016409, 223360574, 223531672, 224480775, 225238694, 227417228, 252459757
|
| Target and Pathway |
| Target(s) |
Catechol-O-methyl-transferase |
Target Info |
Inhibitor |
[1]
|
|---|
|
BioCyc Pathway
|
L-dopa degradation
|
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Dopamine degradation
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Noradrenaline and adrenaline degradation
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KEGG Pathway
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Steroid hormone biosynthesis
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Tyrosine metabolism
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Metabolic pathways
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Dopaminergic synapse
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PANTHER Pathway
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Adrenaline and noradrenaline biosynthesis
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Dopamine receptor mediated signaling pathway
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PathWhiz Pathway
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Tyrosine Metabolism
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WikiPathways
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Methylation Pathways
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Metapathway biotransformation
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Estrogen metabolism
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Biogenic Amine Synthesis
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Dopamine metabolism
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Phase II conjugation
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Neurotransmitter Clearance In The Synaptic Cleft
|
| References |
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
|---|
