Drug General Information
Drug ID
D06OLJ
Former ID
DNC010861
Drug Name
AMG-7160
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551343]
Structure
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2D MOL

3D MOL

Formula
C15H10BrCl4NOS
Canonical SMILES
C1=CC(=CC=C1C(=O)NC(C(Cl)(Cl)Cl)SC2=CC=C(C=C2)Cl)Br
InChI
1S/C15H10BrCl4NOS/c16-10-3-1-9(2-4-10)13(22)21-14(15(18,19)20)23-12-7-5-11(17)6-8-12/h1-8,14H,(H,21,22)
InChIKey
APLQHKFABMHWHP-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily A member 1 Target Info Inhibitor [551343]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 551343Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. J Med Chem. 2010 Jul 22;53(14):5085-107. doi: 10.1021/jm100062h.
Ref 551343Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. J Med Chem. 2010 Jul 22;53(14):5085-107. doi: 10.1021/jm100062h.

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