Drug General Information
Drug ID
D06PUS
Former ID
DNC008721
Drug Name
3-(2-Bromophenyl)-2-thioxo-(1H )-quinazolin-4-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529219]
Structure
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2D MOL

3D MOL

Formula
C14H9BrN2OS
Canonical SMILES
C1=CC=C2C(=C1)C(=O)N(C(=S)N2)C3=CC=CC=C3Br
InChI
1S/C14H9BrN2OS/c15-10-6-2-4-8-12(10)17-13(18)9-5-1-3-7-11(9)16-14(17)19/h1-8H,(H,16,19)
InChIKey
FHKTYFZUNGXFGS-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) CAMP-specific 3',5'-cyclic phosphodiesterase 4B Target Info Inhibitor [529219]
KEGG Pathway Purine metabolism
cAMP signaling pathway
Morphine addiction
NetPath Pathway IL5 Signaling Pathway
IL2 Signaling Pathway
Reactome DARPP-32 events
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
Myometrial Relaxation and Contraction Pathways
Nuclear Receptors Meta-Pathway
Opioid Signalling
References
Ref 529219Eur J Med Chem. 2008 Jul;43(7):1349-59. Epub 2007 Dec 21.CODES, a novel procedure for ligand-based virtual screening: PDE7 inhibitors as an application example.
Ref 529219Eur J Med Chem. 2008 Jul;43(7):1349-59. Epub 2007 Dec 21.CODES, a novel procedure for ligand-based virtual screening: PDE7 inhibitors as an application example.

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