TTD | Drug: D06QRI

Drug General Information
Drug ID	D06QRI
Former ID	DNC003786
Drug Name	7-Dimethylamino-2-phenyl-[1,8]naphthyridin-4-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527090]
Structure		Download 2D MOL 3D MOL
Formula	C16H15N3O
Canonical SMILES	CN(C)C1=NC2=C(C=C1)C(=O)C=C(N2)C3=CC=CC=C3
InChI	1S/C16H15N3O/c1-19(2)15-9-8-12-14(20)10-13(17-16(12)18-15)11-6-4-3-5-7-11/h3-10H,1-2H3,(H,17,18,20)
InChIKey	BEMRWFAUJDRLIY-UHFFFAOYSA-N
PubChem Compound ID	10378184
Target and Pathway
Target(s)	Adenosine A1 receptor	Target Info	Inhibitor	[527090]
KEGG Pathway	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Sphingolipid signaling pathway
	Neuroactive ligand-receptor interaction
	Morphine addiction
NetPath Pathway	TCR Signaling Pathway
NetPath Pathway	RANKL Signaling Pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Adenosine P1 receptors
Reactome	G alpha (i) signalling events
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 527090	J Med Chem. 2004 Jun 3;47(12):3019-31.Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.
Ref 527090	J Med Chem. 2004 Jun 3;47(12):3019-31.Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.

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Drug Information