Drug Information

Drug General Information
Drug ID
D06SMN
Former ID
DNC010109
Drug Name
(R)-2-(4-Benzylphenoxymethyl)pyrrolidine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530549]
Structure
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2D MOL

3D MOL
Formula
C18H21NO
Canonical SMILES
C1CC(NC1)COC2=CC=C(C=C2)CC3=CC=CC=C3
InChI
1S/C18H21NO/c1-2-5-15(6-3-1)13-16-8-10-18(11-9-16)20-14-17-7-4-12-19-17/h1-3,5-6,8-11,17,19H,4,7,12-14H2/t17-/m1/s1
InChIKey
NXNMORHGFGYRDN-QGZVFWFLSA-N
PubChem Compound ID
16222640
Target and Pathway
Target(s) Leukotriene A-4 hydrolase Target Info Inhibitor [530549]
BioCyc Pathway Leukotriene biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Arachidonic acid metabolism
Eicosanoid Synthesis
References
Ref 530549J Med Chem. 2010 Jan 28;53(2):573-85.Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.
Ref 530549J Med Chem. 2010 Jan 28;53(2):573-85.Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.

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