Drug Information
Drug General Information | |||||
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Drug ID |
D06TEO
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Former ID |
DNC001483
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Drug Name |
UCL-1390
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Drug Type |
Small molecular drug
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Indication | Eating disorder; Epilepsy; Pain [ICD9: 307.5, 338,780; ICD10:F50, R52, G89] | Terminated | [1] | ||
Therapeutic Class |
Analgesics
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Company |
University College London
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Structure |
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Download2D MOL |
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Formula |
C13H13N3O
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Canonical SMILES |
C1=CC(=CC=C1C#N)OCCCC2=CN=CN2
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InChI |
1S/C13H13N3O/c14-8-11-3-5-13(6-4-11)17-7-1-2-12-9-15-10-16-12/h3-6,9-10H,1-2,7H2,(H,15,16)
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InChIKey |
XQNBJFUWFIHAMW-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Histamine H3 receptor | Target Info | Antagonist | [2] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
Reactome | Histamine receptors | ||||
G alpha (i) signalling events | |||||
WikiPathways | Monoamine Transport | ||||
GPCRs, Class A Rhodopsin-like | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
References | |||||
REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005172) | ||||
REF 2 | Emerging drugs for eating disorder treatment. Expert Opin Emerg Drugs. 2006 May;11(2):315-36. | ||||
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