Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06TEO
|
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| Former ID |
DNC001483
|
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| Drug Name |
UCL-1390
|
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| Drug Type |
Small molecular drug
|
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| Indication | Eating disorder; Epilepsy; Pain [ICD9: 307.5, 338,780; ICD10:F50, R52, G89] | Terminated | [1] | ||
| Therapeutic Class |
Analgesics
|
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| Company |
University College London
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C13H13N3O
|
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| Canonical SMILES |
C1=CC(=CC=C1C#N)OCCCC2=CN=CN2
|
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| InChI |
1S/C13H13N3O/c14-8-11-3-5-13(6-4-11)17-7-1-2-12-9-15-10-16-12/h3-6,9-10H,1-2,7H2,(H,15,16)
|
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| InChIKey |
XQNBJFUWFIHAMW-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Histamine H3 receptor | Target Info | Antagonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005172) | ||||
| REF 2 | Emerging drugs for eating disorder treatment. Expert Opin Emerg Drugs. 2006 May;11(2):315-36. | ||||
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