Drug General Information
Drug ID
D06WHL
Former ID
DIB004606
Drug Name
NS-257
Synonyms
PD-144216
Indication Cerebrovascular ischaemia [ICD9: 434.91; ICD10:I61-I63] Terminated [545132]
Company
NeuroSearch A/S
Structure
Download
2D MOL

3D MOL

Canonical SMILES
S(=O)(=O)(c1c2c(c3c(/C(=N/O)/C(=O)N3)c1)CN(C2)C)N(C)C
CAS Number
CAS 147750-87-6
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Antagonist [533631]
References
Ref 545132Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002246)
Ref 533631Characterization of the binding of [3H]NS 257, a novel competitive AMPA receptor antagonist, to rat brain membranes and brain sections. J Neurochem. 1995 Sep;65(3):1264-73.

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