Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07BKU
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| Former ID |
DNC008975
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| Drug Name |
A-795614
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C22H25N5O
|
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| Canonical SMILES |
C1CCN(CC1)C2=CC3=C(C=C2)C(CC3)NC(=O)NC4=CC=CC5=C4C=NN5
|
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| InChI |
1S/C22H25N5O/c28-22(24-19-5-4-6-21-18(19)14-23-26-21)25-20-10-7-15-13-16(8-9-17(15)20)27-11-2-1-3-12-27/h4-6,8-9,13-14,20H,1-3,7,10-12H2,(H,23,26)(H2,24,25,28)/t20-/m1/s1
|
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| InChIKey |
SVYGRCSOIPQXGO-HXUWFJFHSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Vanilloid receptor | Target Info | Inhibitor | [1] | |
| Vanilloid receptor 1 | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Inflammatory mediator regulation of TRP channels | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | ||||
| Trk receptor signaling mediated by PI3K and PLC-gamma | |||||
| Reactome | TRP channels | ||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2008 Sep 15;16(18):8516-25. Epub 2008 Aug 7.Tetrahydropyridine-4-carboxamides as novel, potent transient receptor potential vanilloid 1 (TRPV1) antagonists. | ||||
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