Drug General Information |
Drug ID |
D07HNM
|
Former ID |
DNC011864
|
Drug Name |
1,3-Diallyl-3,7-dihydro-purine-2,6-dione
|
Drug Type |
Small molecular drug
|
Indication |
Discovery agent
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Investigative |
[1]
|
Structure |
|
Download
2D MOL
3D MOL
|
Formula |
C11H12N4O2
|
Canonical SMILES |
C=CCN1C2=C(C(=O)N(C1=O)CC=C)NC=N2
|
InChI |
1S/C11H12N4O2/c1-3-5-14-9-8(12-7-13-9)10(16)15(6-4-2)11(14)17/h3-4,7H,1-2,5-6H2,(H,12,13)
|
InChIKey |
NUZFZZOVBJUJQN-UHFFFAOYSA-N
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PubChem Compound ID |
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Target and Pathway |
Target(s) |
Adenosine A2b receptor |
Target Info |
Inhibitor |
[1]
|
Adenosine A1 receptor |
Target Info |
Inhibitor |
[1]
|
Adenosine A2a receptor |
Target Info |
Inhibitor |
[1]
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KEGG Pathway
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Rap1 signaling pathway
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Calcium signaling pathway
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Neuroactive ligand-receptor interaction
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Vascular smooth muscle contraction
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Alcoholismhsa04022:cGMP-PKG signaling pathway
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cAMP signaling pathway
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Sphingolipid signaling pathway
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Morphine addictionhsa04015:Rap1 signaling pathway
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Parkinson's disease
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Alcoholism
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NetPath Pathway
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TGF_beta_Receptor Signaling Pathway
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TCR Signaling PathwayNetPath_11:TCR Signaling Pathway
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RANKL Signaling Pathway
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PANTHER Pathway
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Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
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Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
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Pathway Interaction Database
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C-MYB transcription factor networkhif2pathway:HIF-2-alpha transcription factor network
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PathWhiz Pathway
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Intracellular Signalling Through Adenosine Receptor A2b and AdenosinePW000445:Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
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Reactome
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Adenosine P1 receptors
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G alpha (s) signalling events
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Surfactant metabolismR-HSA-417973:Adenosine P1 receptors
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G alpha (i) signalling eventsR-HSA-187024:NGF-independant TRKA activation
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Surfactant metabolism
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WikiPathways
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Nucleotide GPCRs
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GPCRs, Class A Rhodopsin-like
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GPCR ligand binding
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GPCR downstream signalingWP80:Nucleotide GPCRs
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Monoamine Transport
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NGF signalling via TRKA from the plasma membrane
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GPCR downstream signaling
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GPCRs, Other
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References |
REF 1 | J Med Chem. 1988 Oct;31(10):2034-9.Benzo[1,2-c:5,4-c']dipyrazoles: non-xanthine adenosine antagonists. |