TTD | Drug: D07HTX

Drug General Information
Drug ID	D07HTX
Former ID	DIB016248
Drug Name	GL-331
Drug Type	Small molecular drug
Indication	Colorectal cancer [ICD9: 153, 154; ICD10:C18-C21]		Discontinued in Phase 2	[545233]
Company	University of North Carolina
Structure		Download 2D MOL 3D MOL
Formula	C27H24N2O9
Canonical SMILES	[C@H]12[C@@H]([C@@H](c3c([C@H]1Nc1ccc([N+](=O)[O-])cc1)<br />cc1c(c3)OCO1)c1cc(c(c(c1)OC)O)OC)C(=O)OC2
CAS Number	CAS 127882-73-9
PubChem Compound ID	148091
Target and Pathway
Target(s)	DNA topoisomerase II	Target Info	Modulator	[528299]
References
Ref 545233	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002538)
Ref 528299	GL331, a topoisomerase II inhibitor, induces radiosensitization of human glioma cells. Anticancer Res. 2006 May-Jun;26(3A):2149-56.

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Drug Information