Drug Information

Drug General Information
Drug ID
D07JJS
Former ID
DAP001202
Drug Name
Sulfamethizole
Synonyms
Ayerlucil; Famet; Lucosil; Methazol; Microsul; Proklar; Renasul; Rufol; SULFAMETHIAZOLE; Salimol; Solfametizolo; Sulamethizole; Sulfamethazole; Sulfamethizol; Sulfamethizolum; Sulfamethylthiadiazole; Sulfametizol; Sulfapyelon; Sulfstat; Sulfurine; Sulphamethizole; Sulphamethyltiadiazole; Tetracid; Thidicur;Thiosulfil; Ultrasul; Urocydal; Urodiaton; Urolucosil; Urosulfin; Uroz; Solfametizolo [DCIT]; Sulfa gram; Thiosulfil Forte; RP 2145; VK 53; Sulfamethizolum [INN-Latin]; Sulfametizol [INN-Spanish]; Thiosulfil (TN); Sulfamethizole [USAN:INN:JAN]; Thiosulfil-A-Forte; Sulfamethizole (JP15/USP/INN); N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; N(1)-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; N(sup 1)-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; N(sup 1)-(5-Methyl-1,3,4-thiadiazol-2-yl)-sulfanilamide; 2-(p-Aminobenzenesulfonamido)-5-methylthiadiazole; 2-Methyl-5-sulfanilamido-1,3,4-thiadiazole; 2-Sulfanilamido-5-methyl-1,3,4-thiadiazole; 4-Amino-N-(5-Methyl-1,3,4-Thiadiazol-2-Yl)Benzene-1-Sulfonamide; 4-Amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide; 4-Amino-N-[5-methyl-1,3,4-thiadiazol-2-yl]benzenesulfonamide; 5-Methyl-2-sulfanilamido-1,3,4-thiadiazole
Drug Type
Small molecular drug
Indication Urinary tract infections [ICD9: 599; ICD10:N39.0] Approved [536773]
Therapeutic Class
Antiinfective Agents
Structure
Download
2D MOL

3D MOL
Formula
C9H10N4O2S2
Canonical SMILES
CC1=NN=C(S1)NS(=O)(=O)C2=CC=C(C=C2)N
InChI
1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)
InChIKey
VACCAVUAMIDAGB-UHFFFAOYSA-N
CAS Number
CAS 144-82-1
PubChem Compound ID
5328
PubChem Substance ID
10250, 856011, 4484560, 7847935, 7980701, 8149536, 8153271, 10321215, 11112301, 11335316, 11360555, 11363886, 11366448, 11369010, 11371560, 11374399, 11377172, 11461527, 11466770, 11467890, 11485179, 11486399, 11489138, 11490386, 11492455, 11494806, 14750528, 17389528, 24870514, 24899662, 26611928, 26679913, 26683918, 26747082, 26747083, 29224382, 46508656, 47290998, 47515174, 47662124, 47736323, 47885267, 47959581, 47959582, 48034964, 48416574, 48424124, 48425641, 49698732, 49855021
ChEBI ID
ChEBI:9331
SuperDrug ATC ID
B05CA04; D06BA04; J01EB02; S01AB01
SuperDrug CAS ID
cas=000144821
Target and Pathway
Target(s) Dihydropteroate synthetase Target Info Inhibitor [537676]
References
Ref 536773How many modes of action should an antibiotic have? Curr Opin Pharmacol. 2008 Oct;8(5):564-73. Epub 2008 Jul 30.
Ref 537676Inhibition of bioluminescence in Photobacterium phosphoreum by sulfamethizole and its stimulation by thymine. Biochim Biophys Acta. 1990 Jun 26;1017(3):229-34.

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