Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07KTP
|
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| Former ID |
DNC002364
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| Drug Name |
SCH79687
|
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| Drug Type |
Small molecular drug
|
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| Indication | Central nervous system disease [ICD10:G00-G99] | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C18H16Cl2N4O
|
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| Canonical SMILES |
C1=CC(=CC=C1CC2=CN=CN2)CNC(=O)NC3=CC(=CC(=C3)Cl)Cl
|
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| InChI |
1S/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25)
|
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| InChIKey |
CXNCQFJNXQAFND-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Histamine H3 receptor | Target Info | Antagonist | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | The histamine H3 receptor: from gene cloning to H3 receptor drugs. Nat Rev Drug Discov. 2005 Feb;4(2):107-20. | ||||
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