Drug General Information
Drug ID	D07LCE
Former ID	DNC004196
Drug Name	1,3,9,9a-Tetrahydro-imidazo[4,5-b]quinolin-2-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528087]
Structure		Download 2D MOL 3D MOL
Formula	C10H9N3O
Canonical SMILES	C1C2C(=NC(=O)N2)NC3=CC=CC=C31
InChI	1S/C10H9N3O/c14-10-12-8-5-6-3-1-2-4-7(6)11-9(8)13-10/h1-4,8H,5H2,(H2,11,12,13,14)
InChIKey	KVVGGYBLPPGNMA-UHFFFAOYSA-N
PubChem Compound ID	20200511
Target and Pathway
Target(s)	CGMP-inhibited 3',5'-cyclic phosphodiesterase A	Target Info	Inhibitor	[528087]
KEGG Pathway	Purine metabolism
	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Morphine addiction
Reactome	cGMP effects
	G alpha (s) signalling events
WikiPathways	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 528087	J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.
Ref 528087	J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.

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