Drug General Information
Drug ID	D07LHD
Former ID	DNC005862
Drug Name	1-(2-Dimethylamino-ethyl)-1H-indol-4-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527668]
Structure		Download 2D MOL 3D MOL
Formula	C12H16N2O
Canonical SMILES	CN(C)CCN1C=CC2=C1C=CC=C2O
InChI	1S/C12H16N2O/c1-13(2)8-9-14-7-6-10-11(14)4-3-5-12(10)15/h3-7,15H,8-9H2,1-2H3
InChIKey	PKWAUGJGYFZHOE-UHFFFAOYSA-N
PubChem Compound ID	44404907
Target and Pathway
Target(s)	5-hydroxytryptamine 2C receptor	Target Info	Inhibitor	[527668]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 527668	Bioorg Med Chem Lett. 2005 Oct 15;15(20):4555-9.SAR of psilocybin analogs: discovery of a selective 5-HT 2C agonist.
Ref 527668	Bioorg Med Chem Lett. 2005 Oct 15;15(20):4555-9.SAR of psilocybin analogs: discovery of a selective 5-HT 2C agonist.

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