| Drug General Information |
| Drug ID |
D07LML
|
| Former ID |
DNC003052
|
| Drug Name |
Tosyl-D-Proline
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C12H15NO4S
|
| Canonical SMILES |
CC1=CC=C(C=C1)S(=O)(=O)N2CCCC2C(=O)O
|
| InChI |
1S/C12H15NO4S/c1-9-4-6-10(7-5-9)18(16,17)13-8-2-3-11(13)12(14)15/h4-7,11H,2-3,8H2,1H3,(H,14,15)/t11-/m1/s1
|
| InChIKey |
CGPHGPCHVUSFFA-LLVKDONJSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
838791, 7890853, 10299712, 36888198, 46391854, 46508783, 80164583, 103342657, 104037398, 104634449, 127622192, 132445289, 137245187, 139013270, 160965920, 163121376, 185967745, 188883045, 204357940, 225054118, 228728748, 252151044, 252429450, 252504139
|
| Target and Pathway |
| Target(s) |
Thymidylate synthase |
Target Info |
Inhibitor |
[1]
|
|---|
|
BioCyc Pathway
|
Pyrimidine deoxyribonucleotides biosynthesis from CTP
|
|
Pyrimidine deoxyribonucleotides de novo biosynthesis
|
|
Superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
|
|
Superpathway of pyrimidine deoxyribonucleoside salvage
|
|
DTMP de novo biosynthesis (mitochondrial)
|
|
Pyrimidine deoxyribonucleosides salvage
|
|
KEGG Pathway
|
Pyrimidine metabolism
|
|
One carbon pool by folate
|
|
Metabolic pathways
|
|
PANTHER Pathway
|
De novo pyrimidine deoxyribonucleotide biosynthesis
|
|
Formyltetrahydroformate biosynthesis
|
|
Pathway Interaction Database
|
E2F transcription factor network
|
|
PathWhiz Pathway
|
Pyrimidine Metabolism
|
|
Reactome
|
E2F mediated regulation of DNA replication
|
|
Pyrimidine biosynthesis
|
|
G1/S-Specific Transcription
|
|
WikiPathways
|
Trans-sulfuration and one carbon metabolism
|
|
Retinoblastoma (RB) in Cancer
|
|
One Carbon Metabolism
|
|
Integrated Pancreatic Cancer Pathway
|
|
miR-targeted genes in muscle cell - TarBase
|
|
miR-targeted genes in lymphocytes - TarBase
|
|
miR-targeted genes in leukocytes - TarBase
|
|
miR-targeted genes in epithelium - TarBase
|
|
Metabolism of nucleotides
|
|
Fluoropyrimidine Activity
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
