Drug Information
Drug General Information | |||||
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Drug ID |
D07OCV
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Former ID |
DIB000082
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Drug Name |
HT-0712
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Synonyms |
IPL-455903; Small-molecule PDE4 inhibitors (memory disorders), Inflazyme/Helicon
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Drug Type |
Small molecular drug
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Indication | Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3] | Phase 2 | [547671] | ||
Company |
Dart neuroscience
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Structure |
Download2D MOL |
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Formula |
C25H31NO3
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Canonical SMILES |
[C@H]1(C[C@H](CNC1=O)c1cc(c(cc1)OC)OC1CCCC1)Cc1cc(ccc1)<br />C
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CAS Number |
CAS 617720-02-2
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Type IV phosphodiesterase | Target Info | Inhibitor | [543406] | |
CAMP-specific 3',5'-cyclic phosphodiesterase 4A | Target Info | Inhibitor | [543404] | ||
CAMP-specific 3',5'-cyclic phosphodiesterase 4B | Target Info | Inhibitor | [543405] | ||
NetPath Pathway | IL5 Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
PathWhiz Pathway | Purine Metabolism | ||||
References | |||||
Ref 543404 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1300). | ||||
Ref 543405 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1301). | ||||
Ref 543406 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1303). |
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