Drug General Information
Drug ID	D07PSW
Former ID	DNC004077
Drug Name	N-(4-Phenyl-pyridin-2-yl)-guanidine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526236]
Structure		Download 2D MOL 3D MOL
Formula	C12H12N4
Canonical SMILES	C1=CC=C(C=C1)C2=CC(=NC=C2)N=C(N)N
InChI	1S/C12H12N4/c13-12(14)16-11-8-10(6-7-15-11)9-4-2-1-3-5-9/h1-8H,(H4,13,14,15,16)
InChIKey	LQYVUDQYWIIZAV-UHFFFAOYSA-N
PubChem Compound ID	10219978
Target and Pathway
Target(s)	Tissue-type plasminogen activator	Target Info	Inhibitor	[526236]
KEGG Pathway	Complement and coagulation cascades
	Transcriptional misregulation in cancer
NetPath Pathway	IL5 Signaling Pathway
PANTHER Pathway	Blood coagulation
	Plasminogen activating cascade
Pathway Interaction Database	amb2 Integrin signaling
	Beta2 integrin cell surface interactions
PathWhiz Pathway	Coagulation
Reactome	Dissolution of Fibrin Clot
WikiPathways	Senescence and Autophagy in Cancer
	Complement and Coagulation Cascades
	Endochondral Ossification
	Blood Clotting Cascade
	Dissolution of Fibrin Clot
	Folate Metabolism
	Vitamin B12 Metabolism
	Selenium Micronutrient Network
References
Ref 526236	Bioorg Med Chem Lett. 2002 Jan 21;12(2):181-4.Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 1: 2-Pyridinylguanidines.
Ref 526236	Bioorg Med Chem Lett. 2002 Jan 21;12(2):181-4.Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 1: 2-Pyridinylguanidines.

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