Drug General Information
Drug ID	D07RIQ
Former ID	DNC011272
Drug Name	ADRENOGLOMERULOTROPIN
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[531223]
Structure		Download 2D MOL 3D MOL
Formula	C13H16N2O
Canonical SMILES	CC1C2=C(CCN1)C3=C(N2)C=CC(=C3)OC
InChI	1S/C13H16N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7-8,14-15H,5-6H2,1-2H3
InChIKey	RDUORFDQRFHYBF-UHFFFAOYSA-N
PubChem Compound ID	71028
Target and Pathway
Target(s)	5-hydroxytryptamine 2B receptor	Target Info	Inhibitor	[531223]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 531223	J Med Chem. 2010 Nov 11;53(21):7573-86.Development, validation, and use of quantitative structure-activity relationship models of 5-hydroxytryptamine (2B) receptor ligands to identify novel receptor binders and putative valvulopathic compounds among common drugs.
Ref 531223	J Med Chem. 2010 Nov 11;53(21):7573-86.Development, validation, and use of quantitative structure-activity relationship models of 5-hydroxytryptamine (2B) receptor ligands to identify novel receptor binders and putative valvulopathic compounds among common drugs.

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