Drug Information

Drug General Information
Drug ID
D07TAL
Former ID
DIB019341
Drug Name
compound 20f
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531459], [541085]
Structure
Download
2D MOL
Formula
C23H30N4O4
InChI
InChI=1S/C23H30N4O4/c1-14-20(25-13-26-21(14)30-19-7-6-10-24-15(19)2)29-18-11-16-8-9-17(12-18)27(16)22(28)31-23(3,4)5/h6-7,10,13,16-18H,8-9,11-12H2,1-5H3/t16-,17-/m0/s1
InChIKey
YKEGUYTXACKXKS-IRXDYDNUSA-N
PubChem Compound ID
54585570
PubChem Substance ID
131347420, 138711835, 178102376, 237363811
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [531459]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 531459Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3290-6.
Ref 541085(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5750).
Ref 531459Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3290-6.

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