Drug Information
Drug General Information | |||||
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Drug ID |
D07XTU
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Former ID |
DNC008883
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Drug Name |
Racemic DOI
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Synonyms |
(+/-)DOI
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [538953] | ||
Structure |
Download2D MOL |
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Formula |
C11H16INO2
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InChI |
InChI=1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1
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InChIKey |
BGMZUEKZENQUJY-SSDOTTSWSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | 5-hydroxytryptamine 2B receptor | Target Info | Inhibitor | [529789] | |
5-hydroxytryptamine 2A receptor | Target Info | Inhibitor | [529336] | ||
WikiPathways | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
Monoamine GPCRs | |||||
GPCRs, Class A Rhodopsin-like | |||||
Gastrin-CREB signalling pathway via PKC and MAPK | |||||
GPCR ligand binding | |||||
GPCR downstream signalingWP733:Serotonin Receptor 2 and STAT3 Signaling | |||||
SIDS Susceptibility Pathways | |||||
GPCR downstream signaling | |||||
GPCRs, Other | |||||
References | |||||
Ref 529336 | Bioorg Med Chem. 2008 Apr 15;16(8):4661-9. Epub 2008 Feb 14.The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands. | ||||
Ref 529789 | J Med Chem. 2008 Nov 27;51(22):7094-8.cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia. |
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