Drug Information
Drug General Information | |||||
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Drug ID |
D08CAB
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Former ID |
DIB019698
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Drug Name |
D-aspartic acid
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Synonyms |
D-aspartate
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [541648] | ||
Structure |
Download2D MOL |
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Formula |
C4H7NO4
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InChI |
InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1
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InChIKey |
CKLJMWTZIZZHCS-UWTATZPHSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
3692, 589764, 7886902, 7887197, 8144616, 10220391, 10511076, 11110794, 11113408, 11538062, 15219005, 15297263, 24853106, 26751646, 26751647, 29203865, 44415541, 46504502, 47731299, 47805597, 48029710, 48105253, 49746798, 49831413, 49872021, 57333713, 57581090, 76520148, 85163775, 85165078, 87562145, 90443754, 92298037, 99224355, 102851505, 103199585, 103824708, 104384438, 117544648, 117686986, 124886902, 126525716, 126595472, 126604317, 126609112, 126616645, 126650135, 127638311, 135048939, 135693961
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Target and Pathway | |||||
Target(s) | Glutamate [NMDA] receptor subunit epsilon 2 | Target Info | Agonist | [543838] | |
Glutamate [NMDA] receptor subunit epsilon 1 | Target Info | Agonist | [543837] | ||
GluN2C | Target Info | Agonist | [543839] | ||
GluN2D | Target Info | Agonist | [543840] | ||
NMDA receptor subunit NR1 | Target Info | Agonist | [543836] | ||
KEGG Pathway | Ras signaling pathway | ||||
Rap1 signaling pathway | |||||
cAMP signaling pathway | |||||
Neuroactive ligand-receptor interaction | |||||
Circadian entrainment | |||||
Long-term potentiation | |||||
Glutamatergic synapse | |||||
Dopaminergic synapse | |||||
Alzheimer's disease | |||||
Amyotrophic lateral sclerosis (ALS) | |||||
Huntington's disease | |||||
Cocaine addiction | |||||
Amphetamine addiction | |||||
Nicotine addiction | |||||
Alcoholism | |||||
Systemic lupus erythematosushsa04014:Ras signaling pathway | |||||
Calcium signaling pathway | |||||
PANTHER Pathway | Huntington disease | ||||
Ionotropic glutamate receptor pathway | |||||
Metabotropic glutamate receptor group III pathway | |||||
Metabotropic glutamate receptor group I pathway | |||||
Muscarinic acetylcholine receptor 1 and 3 signaling pathwayP00029:Huntington disease | |||||
Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||||
Pathway Interaction Database | ErbB4 signaling events | ||||
Reelin signaling pathwayreelinpathway:Reelin signaling pathway | |||||
Reactome | EPHB-mediated forward signaling | ||||
Unblocking of NMDA receptor, glutamate binding and activation | |||||
CREB phosphorylation through the activation of CaMKII | |||||
Ras activation uopn Ca2+ infux through NMDA receptor | |||||
RAF/MAP kinase cascadeR-HSA-438066:Unblocking of NMDA receptor, glutamate binding and activation | |||||
RAF/MAP kinase cascadeR-HSA-3928662:EPHB-mediated forward signaling | |||||
RAF/MAP kinase cascade | |||||
WikiPathways | Hypothetical Network for Drug Addiction | ||||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
BDNF signaling pathwayWP666:Hypothetical Network for Drug Addiction | |||||
Alzheimers DiseaseWP706:SIDS Susceptibility Pathways | |||||
Spinal Cord Injury | |||||
BDNF signaling pathway | |||||
Alzheimers Disease | |||||
References | |||||
Ref 543836 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 455). | ||||
Ref 543837 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 456). | ||||
Ref 543838 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 457). | ||||
Ref 543839 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 458). | ||||
Ref 543840 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 459). |
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