Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08FSD
|
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| Former ID |
DIB014788
|
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| Drug Name |
SER-100
|
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| Synonyms |
ORL1 receptor agonists, Zealand Pharma; ZP-120; ZP-120C
|
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| Indication | Heart failure [ICD9: 428; ICD10:I50] | Phase 2 | [1] | ||
| Company |
Zealand Pharma A/S
|
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| Structure |
|
Download2D MOL |
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| Target and Pathway | |||||
| Target(s) | Nociceptin receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | ClinicalTrials.gov (NCT00283361) ZP120 Add-on to Furosemide in Treatment of Acute or Sub-Acute Decompensated Heart Failure. U.S. National Institutes of Health. | ||||
| REF 2 | Clinical pipeline report, company report or official report of Serodus ASA. | ||||
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