Drug Information

Drug General Information
Drug ID
D08GKT
Former ID
DIB020132
Drug Name
KF24345
Synonyms
KF-24345; KF 24345
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467976]
Structure
Download
2D MOL
Formula
C31H38N6O5
InChI
InChI=1S/C31H38N6O5/c1-5-41-26-18-22-24(19-27(26)42-6-2)32-30(36-13-15-40-16-14-36)33-28(22)35-11-9-21(10-12-35)37-29(38)23-17-20(3)7-8-25(23)34(4)31(37)39/h7-8,17-19,21H,5-6,9-16H2,1-4H3
InChIKey
MXOWYPVUVPQDNZ-UHFFFAOYSA-N
PubChem Compound ID
9938824
PubChem Substance ID
79784151, 90306788, 124964068, 178101445, 234493162, 249130091
Target and Pathway
Target(s) Equilibrative nucleoside transporter 1 Target Info Inhibitor [526889]
References
Ref 467976(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4734).
Ref 526889Interaction of the novel adenosine uptake inhibitor 3-[1-(6,7-diethoxy-2-morpholinoquinazolin-4-yl)piperidin-4-yl]-1,6-dimethyl-2,4(1H,3H)-quinazolinedione hydrochloride (KF24345) with the es and ei subtypes of equilibrative nucleoside transporters. J Pharmacol Exp Ther. 2004 Mar;308(3):1083-93. Epub 2003 Nov 21.

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