Drug General Information
Drug ID
D08HQK
Former ID
DAP001431
Drug Name
Tetracaine
Synonyms
Amethocaine; Anetain; Contralgin; Dicain; Dicaine; Dikain; Fissucain; Intercain; Laudocaine; Medicaine; Meethobalm; Metraspray; Mucaesthin; Niphanoid; Pontocaine; Rexocaine; Tetracaina; Tetracainum; Tetrakain; Uromucaesthin; Tetrakain [Czech]; Amethocaine (TN); Diaethylaminoaethanol ester der p-butylaminobenzoesaeure;Diaethylaminoaethanol ester der p-butylaminobenzoesaeure [German]; Medihaler-Tetracaine; Pontocaine (TN); Tetracaina [INN-Spanish]; Tetracaine [USAN:INN]; Tetracainum [INN-Latin]; Dimethylaminoethyl p-butyl-aminobenzoate; Tetracaine (USP/INN); P-Butylaminobenzoyl-2-dimethylaminoethanol; BENZOIC ACID,4-BUTYLAMINO,2-DIMETHYLAMINOETHYL ESTER PANTOCAIN BASE; P-(Butylamino)benzoic acid, 2-(dimethylamino)ethyl ester; BENZOIC ACID, p-(BUTYLAMINO)-, 2-(DIMETHYLAMINO)ETHYL ESTER; Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester; 2-(Dimethylamino)ethyl 4-(butylamino)benzoate; 2-(Dimethylamino)ethyl p-(butylamino)benzoate; 2-Dimethylaminoethylester kyseliny p-butylaminobenzoove; 2-Dimethylaminoethylester kyseliny p-butylaminobenzoove [Czech]; 2-dimethylaminoethyl 4-(butylamino)benzoate; 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester; 4-[Butylamino]benzoic acid-2-[dimethylamino]ethyl ester
Drug Type
Small molecular drug
Indication Spinal anesthesia [ICD9: 338; ICD10:R20.0] Approved [535622]
Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Phase 2 [551871]
Therapeutic Class
Anesthetics
Structure
Download
2D MOL

3D MOL

Formula
C15H24N2O2
Canonical SMILES
CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C
InChI
1S/C15H24N2O2/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3/h6-9,16H,4-5,10-12H2,1-3H3
InChIKey
GKCBAIGFKIBETG-UHFFFAOYSA-N
CAS Number
CAS 94-24-6
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
C05AD02; D04AB06; N01BA03; S01HA03
SuperDrug CAS ID
cas=000094246
Target and Pathway
Target(s) Voltage-gated sodium channel subunit alpha Nav1.8 Target Info Inhibitor [535913]
Reactome Interaction between L1 and Ankyrins
References
Ref 535622Evaluation of a novel topical anesthetic agent for cutaneous laser resurfacing: a randomized comparison study. Dermatol Surg. 2002 Nov;28(11):1004-6; discussion 1006.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 535913Heterologous expression and functional analysis of rat Nav1.8 (SNS) voltage-gated sodium channels in the dorsal root ganglion neuroblastoma cell line ND7-23. Neuropharmacology. 2004 Mar;46(3):425-38.

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