Drug Information

Drug General Information
Drug ID
D08HUC
Former ID
DAP000935
Drug Name
Isoetharine
Synonyms
Bronkosol; Dilabron; Etyprenaline; Etyprenalinum; Isoetarin; Isoetarina; Isoetarine; Isoetarinum; Neoisuprel; Isoetharine Hcl; Win 3406; Bronkometer (TN); Bronkosol (TN); Dey-Lute Isoetharine; Isoetarina [INN-Spanish]; Isoetarine (INN); Isoetarinum [INN-Latin]; Isoetharine (USP); Isoetharine HCl S/F; Isoetharine [USAN:BAN]; 3,4-Dihydroxy-alpha-(1-(isopropylamino)propyl)benzyl alcohol; 4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Approved [538363], [542219]
Therapeutic Class
Bronchodilator Agents
Structure
Download
2D MOL

3D MOL
Formula
C13H21NO3
InChI
InChI=1S/C13H21NO3/c1-4-10(14-8(2)3)13(17)9-5-6-11(15)12(16)7-9/h5-8,10,13-17H,4H2,1-3H3
InChIKey
HUYWAWARQUIQLE-UHFFFAOYSA-N
CAS Number
CAS 530-08-5
PubChem Compound ID
3762
PubChem Substance ID
9265, 4697020, 7979653, 8152380, 11466777, 11467897, 11486413, 15464911, 29222881, 46505384, 47206468, 47440442, 47440443, 47515493, 47810942, 48110635, 49698628, 50064866, 50105269, 50105270, 50398387, 57321982, 85209740, 85788070, 90341304, 103821442, 104304445, 117616915, 123094734, 124749905, 124883527, 124883528, 124883529, 125823582, 128117044, 134224968, 134338210, 134976121, 137087779, 137619493, 160963569, 178103780, 179225230, 223440046, 226439137, 249966774, 252632237
SuperDrug ATC ID
R03AC07; R03CC06
SuperDrug CAS ID
cas=000530085
Target and Pathway
Target(s) Beta-2 adrenergic receptor Target Info Modulator [556264]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Salivary secretion
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta2 adrenergic receptor signaling pathway
Pathway Interaction Database Arf6 trafficking events
Arf6 signaling events
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
Vitamin D Receptor Pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 538363FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 086711.
Ref 542219(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7205).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.