Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08KDK
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| Former ID |
DIB016796
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| Drug Name |
T-2007
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| Synonyms |
DPB sodium; Diphenylbarbituric sodium; Diphenylbarbituric acid (epilepsy), Taro; 5,5-diphenylbarbituric sodium
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| Indication | Epilepsy [ICD10:G40] | Phase 2 | [1] | ||
| Company |
Taro Pharmaceutical Industries Ltd
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
C1(C(=O)NC(=O)NC1=O)(c1ccccc1)c1ccccc1.[Na+]
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| Target and Pathway | |||||
| Target(s) | GABA A receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | |||||
| GABAergic synapse | |||||
| Morphine addiction | |||||
| Nicotine addiction | |||||
| Reactome | Ligand-gated ion channel transport | ||||
| GABA A receptor activation | |||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
| Iron uptake and transport | |||||
| References | |||||
| REF 1 | ClinicalTrials.gov (NCT00939653) T2007-002 Clofarabine, Etoposide, Cyclophosphamide in Relapsed Acute Myelogenous Leukemia (AML). U.S. National Institutes of Health. | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415). | ||||
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